Great Behavioral Tasks can Validate Mouse Models of Autism
In this post I want to discuss an example of when behavioral testing on a mouse model of human disease is done entirely correct. In this case, the right task was chosen for mice, and was developed in very close collaboration with the clinician whose work in humans was being modeled by the mice. This approach, called endophenotyping, actually studies non-core features of autism in a mouse model, but rather models cognitive processing in human autism using a mouse model. … More Great Behavioral Tasks can Validate Mouse Models of Autism